:root{--pb-ground:#d9f7e2;--pb-ink:#242424;--pb-accent:#85521e;--pb-support:#d3ded6;--pb-surface:#fff;--pb-edge:clamp(20px,6.5vw,104px);font-family:'Tuffy',Arial,sans-serif;color:var(--pb-ink);background:var(--pb-surface);font-synthesis:none;scroll-behavior:smooth}
*{box-sizing:border-box}
body{margin:0;font-size:19px;line-height:1.6}
a{color:inherit;text-decoration-thickness:1.5px;text-underline-offset:4px;transition:text-decoration-thickness .18s ease,color .18s ease}
a:hover{text-decoration-thickness:3px;color:var(--pb-accent)}
a:focus-visible{outline:3px solid var(--pb-accent);outline-offset:5px;background:var(--pb-surface);color:var(--pb-ink)}
button,input,select,textarea{font:inherit}
img,svg{max-width:100%}
svg{display:block}
p{margin:0 0 1.25em}
p:last-child{margin-bottom:0}
h1,h2,h3{margin:0;font-weight:400;text-wrap:balance}
h1,h2{font-family:'Chango',Georgia,serif;line-height:1.15;letter-spacing:-.035em}
h3{font-weight:700;font-size:1.3rem;line-height:1.3}
::selection{background:var(--pb-support);color:var(--pb-ink)}
.pb-skip{position:absolute;left:20px;top:-100px;z-index:10;background:var(--pb-surface);padding:12px 20px}
.pb-skip:focus{top:10px}
.pb-masthead{padding:10px var(--pb-edge) 0;background:var(--pb-ground)}
.pb-slot-nav{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));align-items:end;gap:28px;width:560px;height:100px;margin-left:auto}
.pb-slot{display:flex;align-items:center;flex-direction:column;justify-content:space-between;text-decoration:none;line-height:1.15;text-align:center;font-size:17px}
.pb-slot-label{display:flex;gap:7px;align-items:center;white-space:nowrap}
.pb-nav-icon{width:19px;height:19px;stroke-width:1.8;flex:0 0 auto}
.pb-slot::after{content:'';display:block;width:6px;background:var(--pb-accent);flex:1;margin-top:12px;transition:width .18s ease}
.pb-slot:hover::after,.pb-slot[aria-current]::after{width:12px}
.pb-slot-one{height:48px}.pb-slot-two{height:72px}.pb-slot-three{height:96px}
.pb-footing{display:flex;align-items:center;justify-content:space-between;gap:24px;border-bottom:7px solid var(--pb-ink);padding:12px 0 16px}
.pb-name{font-family:'Chango',Georgia,serif;text-decoration:none;font-size:clamp(26px,3.4vw,51px);line-height:1.1;letter-spacing:-.055em;white-space:nowrap}
.pb-name:hover{text-decoration:none;color:var(--pb-accent)}
.pb-brand-fold{width:77px;height:40px;flex:0 0 auto}
.pb-hero{margin:50px var(--pb-edge) 0}
.pb-hero h1{font-size:clamp(42px,5.1vw,76px);max-width:1190px}
.pb-title-fold{position:relative}
.pb-hero-home{isolation:isolate;position:relative;display:grid;justify-items:start;align-content:start;min-height:650px;margin:0;padding:0 var(--pb-edge) 34px;border-bottom:10px solid var(--pb-accent)}
.pb-hero-home .pb-title-fold{width:min(840px,70%);padding:35px 74px 38px 0;background:var(--pb-ground);clip-path:polygon(0 0,94% 0,100% 15%,100% 82%,94% 82%,94% 100%,0 100%)}
.pb-hero-home .pb-title-fold::before{content:'';position:absolute;left:0;top:0;width:64px;height:6px;background:var(--pb-accent)}
.pb-hero-home h1{font-size:clamp(44px,4.05vw,62px);line-height:1.14;max-width:740px}
.pb-home-figure{position:absolute;inset:0;margin:0;z-index:-1}
.pb-aperture{position:absolute;inset:0;display:block;background:var(--pb-support)}
.pb-aperture img{display:block;width:100%;height:100%;object-fit:cover;object-position:center 54%}
.pb-home-figure figcaption{position:absolute;right:var(--pb-edge);bottom:30px;width:252px;background:var(--pb-ground);padding:25px 23px 19px;font-size:16px;line-height:1.4;border-bottom:5px solid var(--pb-accent);clip-path:polygon(50% 0,100% 17%,100% 100%,0 100%,0 17%)}
.pb-hinge-mark{position:absolute;right:calc(var(--pb-edge) + 95px);bottom:151px;width:62px;height:42px;padding:4px;background:var(--pb-ground);animation:pb-unfold .75s ease-out 1}
@keyframes pb-unfold{from{transform:scaleX(.78)}to{transform:scaleX(1)}}
.pb-hero-home .pb-lead{margin:48px 0 0 -24px;padding:25px 28px 22px 24px;width:min(630px,58%);background:var(--pb-ground);font-size:22px;line-height:1.48;border-left:7px solid var(--pb-accent);box-shadow:8px 8px 0 var(--pb-accent)}
.pb-cue{display:inline-flex;gap:14px;align-items:center;font-size:17px;font-weight:700;text-decoration:none;border-bottom:3px solid var(--pb-accent);padding:9px 0 4px;background:var(--pb-ground)}
.pb-hero-home .pb-cue{margin:20px 0 0;padding:9px 16px 7px}
.pb-cue:hover{color:var(--pb-ink);box-shadow:0 4px 0 var(--pb-accent)}
.pb-cue svg{width:20px;height:20px}
.pb-breadcrumb{display:flex;gap:10px;flex-wrap:wrap;margin:30px var(--pb-edge) 0;font-size:16px;list-style:none;padding:0}
.pb-breadcrumb li+li::before{content:'/';margin-right:10px}
.pb-hero-inner{margin-top:30px}
.pb-hero-inner .pb-title-fold{border-left:8px solid var(--pb-accent);padding:0 0 3px 26px}
.pb-hero-inner h1{max-width:1100px;font-size:clamp(40px,4.2vw,62px)}
.pb-hero-inner .pb-lead{font-size:24px;line-height:1.45;max-width:740px;margin:27px 0 0 7%}
.pb-header-photo{margin:44px calc(-1 * var(--pb-edge)) 0 14%;position:relative}
.pb-band{height:280px;background-color:var(--pb-support);background-size:cover;background-position:center 55%;clip-path:polygon(0 0,calc(100% - 48px) 0,100% 48px,100% 100%,0 100%)}
.pb-photo-ipamorelin{background-image:url('one-action.webp')}
.pb-photo-bpc-157{background-image:url('lifted-panel.webp')}
.pb-photo-retatrutide{background-image:url('three-hammers.webp')}
.pb-photo-thymosin-alpha-1{background-image:url('felt-and-wood.webp')}
.pb-photo-compare{background-image:url('whole-action.webp')}
.pb-photo-about{background-image:url('panel-by-chair.webp')}
.pb-header-photo figcaption{position:relative;margin:-25px var(--pb-edge) 0 -40px;padding:18px 25px 18px 40px;max-width:650px;background:var(--pb-ground);font-size:16px;line-height:1.4;border-bottom:5px solid var(--pb-accent)}
.pb-header-photo::before{content:'';position:absolute;z-index:1;top:32px;left:-30px;width:14px;height:110px;background:var(--pb-accent);box-shadow:14px 14px 0 var(--pb-support)}
.pb-bellows{position:relative;margin:95px var(--pb-edge) 0;padding-bottom:56px;isolation:isolate}
.pb-bellows::before{content:'';position:absolute;left:calc(50% - 4px);top:-46px;bottom:0;width:8px;background:var(--pb-accent);z-index:-1}
.pb-leaf{position:relative;margin:0 auto;background:var(--pb-surface);padding:54px clamp(48px,7vw,108px) 62px;border-top:7px solid var(--pb-ink);border-bottom:7px solid var(--pb-support)}
.pb-spread{width:100%;max-width:1150px;box-shadow:14px 14px 0 var(--pb-support)}
.pb-gather{width:70%;max-width:770px;padding:50px clamp(36px,4.5vw,66px) 54px;background:var(--pb-support);border-top-color:var(--pb-accent);border-bottom-color:var(--pb-accent);box-shadow:14px 14px 0 var(--pb-ground)}
.pb-gather::after{content:'';position:absolute;right:0;top:0;border-top:27px solid var(--pb-surface);border-left:27px solid transparent}
.pb-leaf-top{display:grid;grid-template-columns:minmax(0,1fr) 46px;gap:28px;align-items:start;margin-bottom:30px}
.pb-leaf-top h2{font-size:clamp(28px,2.8vw,42px);max-width:870px}
.pb-gather h2{font-size:clamp(27px,2.6vw,36px)}
.pb-panel-icon{width:44px;height:44px;stroke-width:1.7;margin-top:4px;padding:8px;background:var(--pb-ground);border-bottom:4px solid var(--pb-accent)}
.pb-leaf-no{position:absolute;left:-30px;top:-57px;padding:0 8px 6px 0;display:block;background:var(--pb-surface);font-family:'Chango',Georgia,serif;font-size:72px;line-height:1;color:var(--pb-accent)}
.pb-gather .pb-leaf-no{left:-60px;top:28px;background:var(--pb-support);font-size:61px;border-bottom:6px solid var(--pb-accent)}
.pb-copy{max-width:720px}
.pb-copy p{overflow-wrap:break-word}
.pb-copy a{font-weight:700}
.pb-seam{position:relative;max-width:510px;margin:0 auto;padding:56px 30px 62px;font-size:21px;line-height:1.5;background:var(--pb-surface)}
.pb-seam::before,.pb-seam::after{content:'';position:absolute;left:calc(50% - 4px);height:28px;width:8px;background:var(--pb-accent)}
.pb-seam::before{top:0}.pb-seam::after{bottom:0}
.pb-example{padding:28px 0 28px 22px;border-left:5px solid var(--pb-accent);border-top:3px solid var(--pb-surface)}
.pb-example:first-child{padding-top:0;border-top:0}
.pb-example p{margin:10px 0 14px}
.pb-example a{font-size:17px;font-weight:700;display:inline-flex;gap:12px;align-items:center}
.pb-example a svg{height:18px;width:18px;transition:transform .18s ease}
.pb-example a:hover svg{transform:translate(3px,-3px)}
.pb-routing{margin:28px 0 0}
.pb-routing dt{font-weight:700}
.pb-routing dd{margin:8px 0 0}
.pb-reference-list{padding:0;margin:0;list-style:none}
.pb-reference-list li{padding:23px 0;border-top:3px solid var(--pb-surface)}
.pb-reference-list li:first-child{padding-top:0;border-top:0}
.pb-reference-list h3{font-size:21px}
.pb-reference-list .pb-byline{font-size:16px;margin:8px 0}
.pb-reference-list p{margin-bottom:0}
.pb-regulatory-list{max-width:760px}
.pb-regulatory-list li{border-top-color:var(--pb-support)}
.pb-comparison-wrap{max-width:100%;margin-top:34px}
.pb-comparison{width:100%;border-collapse:collapse;font-size:17px;text-align:left}
.pb-comparison caption{text-align:left;font-weight:700;font-size:20px;margin-bottom:14px}
.pb-comparison th,.pb-comparison td{padding:18px 14px;vertical-align:top;border-bottom:3px solid var(--pb-support)}
.pb-comparison thead{background:var(--pb-ground)}
.pb-comparison th:first-child{padding-left:0;width:25%}
.pb-comparison thead th:first-child{padding-left:14px}
.pb-comparison td{width:37.5%}
.pb-afterword{max-width:780px;margin:44px auto 0;padding:0 30px}
.pb-afterword a{display:inline-flex;align-items:center;gap:12px;font-size:21px;font-weight:700}
.pb-afterword svg{width:22px;height:22px}
.pb-colophon{background:var(--pb-ground);margin-top:55px;padding:55px var(--pb-edge) 30px;position:relative;border-top:10px solid var(--pb-accent)}
.pb-footer-intro{display:flex;gap:24px;align-items:center;border-bottom:5px solid var(--pb-ink);padding-bottom:28px;margin-bottom:28px}
.pb-footer-intro img{width:78px;height:46px;flex:0 0 auto}
.pb-footer-intro p{max-width:750px;font-size:21px;line-height:1.4}
.pb-footer-links{display:flex;flex-wrap:wrap;gap:12px 30px;max-width:1050px;list-style:none;padding:0;margin:0}
.pb-footer-links a{font-size:17px}
.pb-copyright{font-size:16px;margin:28px 0 0}
.pb-error{padding:65px 0 80px;max-width:800px}
.pb-error p{font-size:24px;margin:28px 0}
@media(min-width:1600px){.pb-hero-inner,.pb-bellows,.pb-breadcrumb{max-width:1340px;margin-left:auto;margin-right:auto}.pb-hero-home .pb-title-fold{width:850px}}
@media(max-width:1050px){.pb-hero-home .pb-title-fold{width:80%;padding-right:60px}.pb-hero-home h1{font-size:49px}.pb-hero-home .pb-lead{width:65%;font-size:21px}.pb-home-figure figcaption{width:220px}.pb-hinge-mark{right:calc(var(--pb-edge) + 79px);bottom:148px}.pb-leaf{padding-left:62px;padding-right:48px}.pb-gather{width:82%}.pb-leaf-top h2{font-size:32px}.pb-header-photo{margin-left:8%}.pb-name{font-size:clamp(24px,4.5vw,44px)}.pb-brand-fold{width:58px}}
@media(max-width:700px){
 :root{--pb-edge:20px;scroll-behavior:auto}
 body{font-size:18px;line-height:1.57}
 .pb-masthead{padding-top:3px}
 .pb-slot-nav{width:100%;height:49px;gap:6px;margin:0}
 .pb-slot{height:auto;font-size:14px;line-height:18px;gap:3px;justify-content:flex-end;padding-bottom:0}
 .pb-slot-label{gap:0;white-space:normal}
 .pb-nav-icon{display:none}
 .pb-slot::after{display:none}
 .pb-slot::before{content:'';width:5px;background:var(--pb-accent);display:block;flex:0 0 auto}
 .pb-slot-one::before{height:12px}.pb-slot-two::before{height:20px}.pb-slot-three::before{height:28px}
 .pb-footing{padding:8px 0 9px;border-bottom-width:5px;gap:0}
 .pb-name{font-size:clamp(16px,5.05vw,22px);letter-spacing:-.055em;line-height:1.1}
 .pb-brand-fold{display:none}
 .pb-hero{margin-top:28px}
 .pb-hero-home{margin:0;min-height:760px;padding:0 20px 270px;border-bottom-width:7px}
 .pb-hero-home .pb-title-fold{width:100%;margin:0;padding:27px 24px 25px 0;clip-path:polygon(0 0,94% 0,100% 9%,100% 91%,94% 91%,94% 100%,0 100%)}
 .pb-hero-home h1,.pb-hero-inner h1{font-size:34px;line-height:1.17;letter-spacing:-.035em;overflow-wrap:break-word}
 .pb-hero-home .pb-lead{width:calc(100% - 9px);margin:20px 0 0;padding:20px 18px;font-size:20px;line-height:1.45;border-left-width:5px;box-shadow:7px 7px 0 var(--pb-accent)}
 .pb-hero-home .pb-cue{margin:19px 0 0;padding:8px 11px;font-size:16px;gap:8px}
 .pb-aperture img{object-position:center bottom}
 .pb-home-figure figcaption{right:20px;bottom:20px;padding:22px 18px 16px;width:220px;font-size:15px}
 .pb-hinge-mark{right:99px;bottom:131px;width:62px;height:42px}
 .pb-breadcrumb{margin-top:23px;font-size:15px;gap:7px}
 .pb-breadcrumb li+li::before{margin-right:7px}
 .pb-hero-inner{margin-top:22px}
 .pb-hero-inner .pb-title-fold{border-left-width:5px;padding-left:15px}
 .pb-hero-inner .pb-lead{font-size:21px;margin:22px 0 0}
 .pb-header-photo{margin:28px -20px 0 15px}
 .pb-band{height:190px;clip-path:polygon(0 0,calc(100% - 30px) 0,100% 30px,100% 100%,0 100%)}
 .pb-header-photo::before{width:8px;height:50px;left:-15px;top:20px;box-shadow:7px 7px 0 var(--pb-support)}
 .pb-header-photo figcaption{margin:-14px 20px 0 -15px;padding:15px 18px;font-size:15px}
 .pb-bellows{margin-top:80px;padding-bottom:20px}
 .pb-bellows::before{width:4px;left:calc(50% - 2px);top:-25px}
 .pb-leaf{width:calc(100% - 7px);padding:35px 21px 36px;border-top-width:5px;border-bottom-width:5px;box-shadow:7px 7px 0 var(--pb-support)}
 .pb-gather{width:calc(100% - 23px);padding:34px 20px 34px;box-shadow:7px 7px 0 var(--pb-ground)}
 .pb-gather::after{border-top-width:20px;border-left-width:20px}
 .pb-leaf-top{gap:12px;grid-template-columns:minmax(0,1fr) 28px;margin-bottom:24px}
 .pb-leaf-top h2,.pb-gather h2{font-size:26px;line-height:1.2;letter-spacing:-.04em;overflow-wrap:break-word}
 .pb-panel-icon{height:28px;width:28px;margin-top:2px;padding:3px;border-bottom-width:3px}
 .pb-leaf-no,.pb-gather .pb-leaf-no{position:relative;top:auto;left:auto;display:block;width:max-content;font-size:36px;border:0;margin:-59px 0 20px;padding:0 8px 0 0;background:inherit}
 .pb-seam{max-width:100%;margin:0 12px;padding:39px 18px 42px;font-size:19px}
 .pb-seam::before,.pb-seam::after{height:18px;width:4px;left:calc(50% - 2px)}
 .pb-example{padding:23px 0 23px 15px;border-left-width:4px}.pb-example h3{font-size:22px}
 .pb-copy a{overflow-wrap:anywhere}
 .pb-reference-list h3{font-size:20px}
 .pb-reference-list .pb-byline{font-size:16px}
 .pb-comparison{font-size:17px}
 .pb-comparison thead{display:none}
 .pb-comparison tbody,.pb-comparison tr,.pb-comparison td,.pb-comparison th{display:block;width:100%}
 .pb-comparison tr{padding:18px 0;border-top:4px solid var(--pb-support)}
 .pb-comparison th,.pb-comparison td{border:0;padding:5px 0}
 .pb-comparison td::before{content:attr(data-pb-label);display:block;font-weight:700;font-size:16px}
 .pb-afterword{padding:0 20px;margin-top:28px}
 .pb-afterword a{font-size:19px}
 .pb-colophon{margin-top:34px;padding-top:34px;border-top-width:7px}
 .pb-footer-intro{gap:14px;align-items:flex-start;padding-bottom:22px}
 .pb-footer-intro img{width:39px;height:26px;margin-top:4px}
 .pb-footer-intro p{font-size:19px}
 .pb-footer-links{gap:12px 24px}
 .pb-copyright{font-size:15px}
 .pb-error{padding:30px 0 60px}.pb-error p{font-size:21px}
}
@media(prefers-reduced-motion:reduce){:root{scroll-behavior:auto}*,*::before,*::after{animation:none!important;transition:none!important}}
